5-甲氧基-2-苯并咪唑硫醇

2-Mercapto-5-methoxybenzimidazole is used in the preparation of COX-2 inhibitors. It is also employed in the preparation of compounds such as 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfonyl]-1H-benzimidazole and 5-methoxy-2-[[(4-methoxy-3,5-dimethylpyridin-2-yl-1-oxide)methyl]sulfonyl]-1H-benzimidazole. Further, it acts as a hetercocyclic building block and serves as an intermediate of drug omeprazole.

Air sensitive. Store in a cool place. Incompatible with strong oxidizing agents, acids, bases and reducing agents.

MFCD00134581

253-326-2

C₈H₈N₂OS

180.23

255-259°

Ambient temperatures.

Powder

Soluble in dimethyl sulfoxide. Slightly soluble in methanol. Insoluble in water.

3605123

36/37/38
Irritating to eyes, respiratory system and skin.

26-37
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

否

 

H315-H319-H335
Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.